Domain 26 of Tropoelastin Plays a Dominant Role in Association by Coacervation
نویسندگان
چکیده
منابع مشابه
Glycosaminoglycans mediate the coacervation of human tropoelastin through dominant charge interactions involving lysine side chains.
Following cellular secretion into the extracellular matrix, tropoelastin is transported, deposited, and cross-linked to make elastin. Assembly by coacervation was examined for an isoform of tropoelastin that lacks the hydrophilic domain encoded by exon 26A. It is equivalent to a naturally secreted form of tropoelastin and shows similar coacervation performance to its partner containing 26A, the...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2000
ISSN: 0021-9258
DOI: 10.1074/jbc.m004265200